Vielight Research & Collaboration

  • Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial

Institutes – University of California San Francisco & the Veterans Affairs USA

[ Published Study Link (Photomedicine and Laser Surgery)

    (10 participants | 1 year | Published)
  • Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study

Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

[ Published Study Link (Nature, Scientific Reports)

    (20 participants | 2 years | Published)
  • Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report

Co-authoring institutes – Harvard Medical School, Boston University School of Medicine

[ Published Study (Photomedicine and Laser Surgery) ]

    (5 participants | 1 year | Published)
  • Evaluation of dose of Photobiomodulation (Light) Therapy and Physiotherapy for Improving Quality of Life Outcomes and Mobility in Parkinson’s Disease (Pilot)

[ Clinical Trial Information Link (Australian New Zealand Clinical Trial Registry) ]

    (16 participants | 1.5 years | Starting)
  • Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer’s Disease

[ Clinical Trial Information Link ( – subsidiary of the US National Library of Medicine) ]

    (16 participants | 1.5 years | Starting)
  • Vielight Neuro RX Gamma – Pivotal Phase III Clinical Trial

[ Clinical Trial Information Link ( – subsidiary of the US National Library of Medicine) ]

    (228 participants | 3 years | Ongoing)
  • Complementary EEG Evidence for a Significantly Improved Alzheimer’s Disease Case after PhotobiomodulationTreatment

[ Poster Link (Presented at: Alzheimer’s Association International Conference, July 14-20, 2017) ]

Disclaimer: The research links below are independent information sources about photobiomodulation. No representation is made regarding Vielight devices or their capabilities.

Brain Photobiomodulation

  • Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins

Medical College of Wisconsin : [ Link ]

  • Neuroprotective effects of photobiomodulation : Evidence from assembly/disassembly of the Cytoskeleton

University of Sydney : [ Link ]

  • Molecular Targets for Photobiomodulation

Stanford University School of Medicine : Link ]

  • Red and NIR light dosimetry in the human deep brain

Institute of Chemical Sciences and Engineering, Switzerland : [ Link 1 | Link 2 ]

  • Transcranial Red and Near Infrared Light Penetration in Cadavers

State University of New York Downstate Medical Center : [ Link ]

  • Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue

Oregon Health and Science University : [ Link 1 | Link 2 ]

  • Review of brain photobiomodulation : targeting brain metabolism, inflammation, oxidative stress, and neurogenesis

Massachusetts General Hospital : [ Link ]

  • Shining light on the head : Photobiomodulation for brain disorders

Massachusetts General Hospital : [ Link ]

  • Augmentation of cognitive brain functions with transcranial lasers

Department of Psychology and Institute for Neuroscience, University of Texas : Link ]

  • Neurological and psychological applications of transcranial lasers and LEDs

Department of Neurology and Neurotherapeutics, University of Texas : Link ]

  • Photobiomodulation – mitochondrial ROS generation and calcium increase in neuronal synapses.

Lin-Kou Medical Center, Taiwan : [ Link ]

  • Infrared neural stimulation and functional recruitment of the peripheral Nerve

Department of Biomedical Engineering, Case Western Reserve University : [ Link ]

  • Photobiomodulation directly benefits primary neurons functionally inactivated by toxins

Dept. of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin : [ Link ]

  • A novel method of applying NIR light intracranially, impact on dopaminergic cell survival

University of Sydney, CEA-Leti : [ Link ]

Low Level Blood Irradiation

  • How Photons Modulate Wound Healing via the Immune System

King’s College London (KCL), University of London : [ Link ]

  • Randomized, Double-Blind, and Placebo-Controlled Clinic Report of Intranasal Low-Intensity Laser Therapy on Vascular Diseases

Ministry of Education, Key Laboratory of Laser Life Science, China : [ Link ]

  • Blood Laser Irradiation : current state and future perspectives

ABER Institute, Helsinki, Finland : [ Link ]

  • Intravenous Laser Blood Irradiation

MH Weber : [ Link ]

  • Applications of Intranasal Low Intensity Laser Therapy In Sports Medicine

Journal of Innovative Optical Health Sciences, World Scientific : [ Link ]

  • Formation of gigantic mitochondria in human blood lymphocytes under the effect of a low level laser source

Institute on Laser and Informatic Technologies of Russian Acad. : [ Link ]

  • Light-harvesting chlorophyll pigments enable mammalian mitochondria to capture photonic energy and produce ATP

Columbia University Medical Center, New York : [ Link ]

  • Irradiation with He-Ne laser increases ATP level in cells cultivated in vitro

National Cancer Research Centre of the Academy of Medicine and Science : [ Link ]

Photobiomodulation Mechanisms

    • Mitochondrial Mechanisms of Photobiomodulation – Multiple Roles of ATP : Link ]
    • Therapeutic Photobiomodulation: Nitric Oxide and a Novel Function of Mitochondrial Cytochrome C Oxidase : [ Link ]
  • Mechanisms of Low Level Light Therapy : [ Link ]
  • Basic Photomedicine : [ Link ]
  • The Nuts and Bolts of Low Level Light Therapy : [ Link ]